10 ENGLISH BOOKS RELATING TO «ADENOVIRAL»
Discover the use of
adenoviral in the following bibliographical selection. Books relating to
adenoviral and brief extracts from same to provide context of its use in English literature.
1
Adenoviral Vectors for Gene Therapy
The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to ...
David T. Curiel, Joanne T. Douglas, 2002
2
Investigation of
Adenoviral Gene Transfer and Associated ...
Despite the long-term efficacy and reduced adaptive immune response profile, toxicities resulting from Ad capsid interactions with the innate immune system limit Ad gene transfer in vivo.
3
Inhibition of Vascular Smooth Muscle Cell Proliferation in ...
Chapter 1 Adenoviral transfer and expression of VIP gene in rat aortic and
pulmonary artery smooth muscle cells, effect on proliferation and phenotype
Introduction VIP has been shown to have an antiproliferative effect on vascular
smooth ...
Rose-Claire St. Hilaire, 2007
4
Adenoviral Protein E3-19K and Immune System Evasion-the ...
Hong Liu. theHLA-A*30 and -A*31 subtypes. Based on this analysis, it can be
concluded that the vast majority of HLA-A alleles are expected to be strongly
targeted and retained by E3-19K in the ER of Ad-infected cells. The fact that the
MHC ...
5
Viral Vectors for Treating Diseases of the Nervous System
If there is a risk of adenoviral encephalitis it will have to be carefully considered at
a time adenovirus vector is directly administered into the brain. It is clear that
many more studies will be required to clarify the origins of neurotoxicity after
direct ...
6
Gene Therapy in Lung Disease
adenoviral vectors is hampered by development of neutralizing antiadenoviral
antibodies, which can significantly reduce repeat transduction of epithelial cells (
23,54). This would likely be less relevant for use of adenoviral vectors in acute ...
Schneider et al. showed absence of immune responses against adenoviral
capsid proteins and the transgene product (Schneider et al. 2002). However,
even in one study in which neutralizing antibodies against capsid proteins were
detected, ...
8
Targeting
Adenoviral Vectors to Cells Expressing EGFRvIII ...
Current adenovirus retargeting strategies are unable to target the virus to specific cell types.
3. Production of Adenoviral Vectors Production of adenoviral vectors requires a
two-step procedure, entailing first the generation of a vector genomic DNA with
the sequence of interest and later its replication and packaging to obtain
infectious ...
10
Gene Therapy for Acute and Acquired Diseases
Adenoviral Vectors The adenoviral vector has distinct advantages of high titers
and the highest level of expression of transgene among available vectors. The
adenoviral vector has a significant advantage in delivering relatively large genes
...
10 NEWS ITEMS WHICH INCLUDE THE TERM «ADENOVIRAL»
Find out what the national and international press are talking about and how the term
adenoviral is used in the context of the following news items.
AIDS: HIV Vaccine Results In Monkeys Encouraging
The vaccine consists of two parts: the first leverages Janssen's AdVac, an adenoviral vectors technology, which involves a cold-causing virus ... «ReliaWire, Jul 15»
Granzyme B mediated function of Parvovirus B19-specific CD4 + T …
Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition. EMBO J 2007; 26: ... «Nature.com, Jul 15»
Molecular genetics of coronary artery disease
Article | PubMed | CAS |; Maxwell, K. N. & Breslow, J. L. Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein ... «Nature.com, Jul 15»
Vascular endothelial growth factor receptor-3 is a novel target to …
... of the adenoviral vectors intravenously through the tail vein. On day 22, the mice were assessed using a conventional peritoneal equilibration ... «Nature.com, Jun 15»
KLF4 regulates adult lung tumor-initiating cells and represses K-Ras …
Although adenoviral infection could induce inflammation, which is associated with bronchiolar hyperplasia, Klf4 deletion and K-ras mutation in ... «Nature.com, Jun 15»
Genetic evidence in the mouse solidifies the calcium hypothesis of …
Another possibility could be adenoviral gene therapy to express dnTRPC or dnTRPV channels selectively in skeletal muscle, which appears to ... «Nature.com, Jun 15»
US FDA grants Orphan Drug status to PNP Therapeutics's Gedeptin
... to PNP Therapeutics Inc's lead product candidate Gedeptin (adenoviral vector expressing E. coli purine nucleoside phosphorylase gene) for ... «pharmabiz.com, Jun 15»
PNP Therapeutics Inc. Receives Orphan Drug Status for Gedeptin
... and Drug Administration has granted orphan drug status to Gedeptin™, the Company's lead product candidate (adenoviral vector expressing ... «PR Newswire, Jun 15»
Transient blocking of NK cell function with small molecule inhibitors …
When NK cells are co-cultured with helper-dependent adenoviral (HD-Ad) vector activated macrophages, IFN-γcytokine expression by NK cells ... «7thSpace Interactive, Jun 15»
GenVec And Washington University at St. Louis Form Collaboration …
The company is a pioneer in the design, testing and manufacture of adenoviral-based product candidates that can deliver on the promise of ... «PipelineReview.com, Jun 15»
