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Meaning of "deprenyl" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF DEPRENYL

deprenyl  [ˈdɛprəˌnɪl] play
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GRAMMATICAL CATEGORY OF DEPRENYL

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Deprenyl is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES DEPRENYL MEAN IN ENGLISH?

Selegiline

Selegiline is a drug used for the treatment of early-stage Parkinson's disease, depression and dementia. In normal clinical doses it is a selective irreversible MAO-B inhibitor. However, in larger doses it loses its specificity and also inhibits MAO-A. Dietary restrictions are common for MAOI treatments, but special dietary restrictions for lower doses have been found to be unnecessary, and dietary restrictions appear to be unnecessary at standard doses when selegiline is taken as Emsam, the transdermal patch form, as no adverse events due to diet have ever been reported with Emsam. The drug was discovered by József Knoll et al. in Hungary. Selegiline belongs to a class of drugs called phenethylamines. Selegiline is a levomethamphetamine derivative with a propargyl group attached to the nitrogen atom.

Definition of deprenyl in the English dictionary

The definition of deprenyl in the dictionary is a drug used to treat senile dementia, Parkinson's, Alzheimer's and depression, by acting as a monoamine oxidase inhibitor.

WORDS THAT RHYME WITH DEPRENYL


anil
ˈænɪl
antimonyl
ˈæntɪmənɪl
ethynyl
ɛˈθaɪnɪl
manille
mæˈnɪl
nil
nɪl
nill
nɪl
nonyl
ˈnɒnɪl
penill
pɪˈnɪl
pennill
ˈpenɪl
polyvinyl
ˌpɒlɪˈvaɪnɪl
succinyl
ˈsʌksɪnɪl
sulfonyl
ˈsʌlfənɪl
sulphinyl
ˈsʌlfənɪl
sulphonyl
ˈsʌlfənɪl
thionyl
ˈθaɪənɪl
uranyl
ˈjʊərənɪl
vinyl
ˈvaɪnɪl

WORDS THAT BEGIN LIKE DEPRENYL

depreciatingly
depreciation
depreciative
depreciator
depreciatory
depredate
depredation
depredator
depredatory
deprehend
depress
depressant
depressed
depressible
depressing
depressingly
depression
depressive
depressively
depressiveness

WORDS THAT END LIKE DEPRENYL

acetyl
adenyl
alanyl
alkyl
benzenecarbonyl
beryl
biphenyl
butyl
carbonyl
Chernobyl
dimethyl
diphenyl
ethyl
fentanyl
hwyl
hydroxyl
methyl
phenyl
polychlorinated biphenyl
propenyl

Synonyms and antonyms of deprenyl in the English dictionary of synonyms

SYNONYMS

Translation of «deprenyl» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF DEPRENYL

Find out the translation of deprenyl to 25 languages with our English multilingual translator.
The translations of deprenyl from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «deprenyl» in English.

Translator English - Chinese

丙炔苯丙胺
1,325 millions of speakers

Translator English - Spanish

deprenyl
570 millions of speakers

English

deprenyl
510 millions of speakers

Translator English - Hindi

deprenyl
380 millions of speakers
ar

Translator English - Arabic

deprenyl
280 millions of speakers

Translator English - Russian

депренил
278 millions of speakers

Translator English - Portuguese

deprenyl
270 millions of speakers

Translator English - Bengali

deprenyl
260 millions of speakers

Translator English - French

déprényl
220 millions of speakers

Translator English - Malay

Deprenyl
190 millions of speakers

Translator English - German

deprenyl
180 millions of speakers

Translator English - Japanese

デプレニール
130 millions of speakers

Translator English - Korean

deprenyl
85 millions of speakers

Translator English - Javanese

Deprenyl
85 millions of speakers
vi

Translator English - Vietnamese

deprenyl
80 millions of speakers

Translator English - Tamil

deprenyl
75 millions of speakers

Translator English - Marathi

डिफरिन
75 millions of speakers

Translator English - Turkish

deprenil
70 millions of speakers

Translator English - Italian

deprenyl
65 millions of speakers

Translator English - Polish

deprenyl
50 millions of speakers

Translator English - Ukrainian

депренил
40 millions of speakers

Translator English - Romanian

deprenilului
30 millions of speakers
el

Translator English - Greek

δεπρενύλης
15 millions of speakers
af

Translator English - Afrikaans

deprenyl
14 millions of speakers
sv

Translator English - Swedish

deprenyl
10 millions of speakers
no

Translator English - Norwegian

deprenyl
5 millions of speakers

Trends of use of deprenyl

TRENDS

TENDENCIES OF USE OF THE TERM «DEPRENYL»

The term «deprenyl» is normally little used and occupies the 117.192 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Little used
45
/100
The map shown above gives the frequency of use of the term «deprenyl» in the different countries.
Principal search tendencies and common uses of deprenyl
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «deprenyl».

FREQUENCY OF USE OF THE TERM «DEPRENYL» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «deprenyl» during the past 500 years. Its implementation is based on analysing how often the term «deprenyl» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about deprenyl

EXAMPLES

10 ENGLISH BOOKS RELATING TO «DEPRENYL»

Discover the use of deprenyl in the following bibliographical selection. Books relating to deprenyl and brief extracts from same to provide context of its use in English literature.
1
How Selegiline ((-)-Deprenyl) Slows Brain Aging
Knoll, J (1978), 'The possible mechanism of action of (-)deprenyl in Parkinson's disease', Journal Neural Transmission, 43:177-198. Knoll, J (1981a), 'Can the suicide inactivation of MAO by deprenyl explain its pharmacological effects?', In: TP ...
Joseph Knoll, 2012
2
Oxidative Stress and Neuroprotection
Deprenyl: from chemical synthesis to neuroprotection K. Magyar1;2, M. Pa ́lfi2, V. Jenei3, E ́. Szo ̈k}oo}1 1 Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary 2 Neurochemical Research Unit, Hungarian ...
S.H. Parvez, Peter Riederer, 2006
3
Current Medicinal Chemistry
sensitive methods, such as PET (positron emission tomography, using 11C labeled compound) or autoradiography (using 14C-labeling) are needed for localization and determination of deprenyl metabolites in various brain regions.
4
Neuropsychiatric Disorders: An Integrative Approach
Pharmacokinetic studies of (2)-deprenyl and some of its metabolites in mouse K. Magyar1;3, I. Szatma ́ry2, G. Szebeni2, J. Lengyel3 1 Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary 2 Metabolism and ...
Manfred Gerlach, Jürgen Deckert, Kay Double, 2007
5
Radiopharmaceuticals: Chemistry and Pharmacology
The labeled enantiomers of deprenyl were used to examine the retention of carbon- 11 labeled L-deprenyl in more detail. Deprenyl contains an assymetric carbon atom and the D-deprenyl and L-deprenyl are synthesized from [S]-(+)- ...
Adrain D. Nunn, 1992
6
Free Radicals in Brain Pathophysiology
but not by deprenyl, even at high concentrations. In contrast, excess cold clorgy- line completely blocked the labeling of both bands with 'H-clorgyline. Thus, mitochondria contain a protein that can specifically interact with clorgyline but is ...
Giuseppe Poli, 2000
7
Veterinary Pharmacology and Therapeutics
L-DEPRENYL Chemistry and Mechanism of Action. L-Deprenyl hydrochloride ( selegiline hydrochloride) is phenylisopro- pyl-TV-methylpropinylamine (Fig. 30.9) and is an irreversible inhibitor of monoamine oxidase B. L-Deprenyl is thought to  ...
Jim E. Riviere, Mark G. Papich, 2009
8
Neurochemistry: Cellular, Molecular, and Clinical Aspects ; ...
Deprenyl and pF-deprenyl were quantitated by GC/MS with a 30-m capillary column (DB-225), selected ion monitoring (M + 1), and positive chemical ionization using methane/ammonia (95:5) as the reactant gas. When deprenyl was to be ...
Albert Teelken, J. Korf, Jaap Korf, 1997
9
Principles of Treatment in Parkinson's Disease
nigra did not significantly change the MPP+-induced dopamine depletion. The authors concluded that L-deprenyl might possess a unique neuroprotective action on nigral neurons against MPP+ toxicity independent of the MAO-B inhibition.
Anthony Henry Vernon Schapira, Charles Warren Olanow, 2005
10
The Brain and Its Self: A Neurochemical Concept of the ...
Age-related deterioration of the striatal machinery is a continuum and any precisely determined short segment of it is sufficient to measure the rate of decline in the presence or absence of (−)-deprenyl. As a matter of fact, in the DATATOP ...
Joseph Knoll, 2005

10 NEWS ITEMS WHICH INCLUDE THE TERM «DEPRENYL»

Find out what the national and international press are talking about and how the term deprenyl is used in the context of the following news items.
1
Can anything be done about Parkinson's Disease?
Selegiline (aka deprenyl, or Emsam) was a standard treatment for PD in the 1980s. It has since fallen out of favor because of inconsistent ... «h+ Magazine, Jul 15»
2
Anti-Aging Pills in the News
I have written about my experience with low-dose deprenyl, which I take for life extension, but which also loosens my inhibitions a bit in a way ... «h+ Magazine, Mar 15»
3
New Trends in Anti-Aging Medicine
Drugs such as deprenyl have been used as a preventative for this loss by increasing and stabilizing dopamine levels when taken in small but ... «Onislam.net, Jan 15»
4
Symptoms, signs to watch for as pets age
Also targeting brain health is the drug Anipryl. Anipryl is L-deprenyl. A form of this is used in humans to treat Parkinson's disease, Alzheimer's, ... «The Northwest Florida Daily News, Nov 14»
5
An Easy Way to Help Your Dog Live Longer
Researchers on the human side of things have noticed that Parkinson disease patients who take L-deprenyl not only experienced fewer ... «Philly.com, Sep 14»
6
During World Alzheimer's Month, Take Steps to Care for Your Most …
Some pharmaceuticals may help enhance cerebral blood flow and increase concentration, including Hydergine, Deprenyl and Prozac, to name ... «Your Houston News, Aug 14»
7
That Hang-Dog Look
... and Anipryl, also known as selegiline or L-deprenyl, for cognitive dysfunction. Others are nortriptyline, Elavil (amitriptyline) and doxepin. «New York Times, May 14»
8
Public Release: 11-Mar-2014 Higher levels of CSF alpha-synuclein …
Researchers were able to access CSF samples from the deprenyl and tocopherol antioxidative therapy of Parkinsonism (DATATOP) study, ... «EurekAlert, Mar 14»
9
The Unsuccessful Search for a Functional Aphrodisiac
“Long-Lasting, True Aphrodisiac Effect of (-)-deprenyl in Sexually Sluggish Old Male Rats.” “Purification and Analysis of a Proteinaceous ... «Pacific Standard, Feb 14»
10
Anti-aging Anti-depressants
Of these, I find Deprenyl most problematic, because it is at once the only one of these ... I wrote up the story of Deprenyl on this page last March. «ScienceBlog.com, Dec 13»

REFERENCE
« EDUCALINGO. Deprenyl [online]. Available <https://educalingo.com/en/dic-en/deprenyl>. May 2024 ».
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