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Meaning of "methoxyflurane" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF METHOXYFLURANE

methoxyflurane  [mɪˌθɒksɪˈflʊəreɪn] play
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GRAMMATICAL CATEGORY OF METHOXYFLURANE

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Methoxyflurane is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES METHOXYFLURANE MEAN IN ENGLISH?

Methoxyflurane

Methoxyflurane, formerly marketed as Penthrane by Abbott Laboratories, is a halogenated ether that was in clinical use as a volatile inhalational anesthetic from its introduction by Joseph F. Artusio et al in 1960 until the late 1970s. It was first synthesized in the late 1940s by William T. Miller and his team of chemists following their involvement in the Manhattan Project. Methoxyflurane is an extremely potent and highly lipid soluble anesthetic agent, characterized by very slow induction and emergence times. It is non-flammable, has relatively mild hemodynamic effects, and it does not predispose the heart to rhythm disturbances. It is however a significant respiratory depressant. Methoxyflurane has powerful analgesic properties at well below full anesthetic doses. It was utilized in self-administration devices for obstetric analgesia, in a manner that foreshadowed the patient-controlled analgesia infusion pumps of today. The biodegradation of methoxyflurane produces inorganic fluoride and dichloroacetic acid. The combined effects of these two compounds may be responsible for the toxicity of methoxyflurane to some of the major organs of the human body.

Definition of methoxyflurane in the English dictionary

The definition of methoxyflurane in the dictionary is a compound, C3H4Cl2F2O, that was formerly used as an inhalational anaesthetic but was withdrawn due to adverse effects to the kidneys.

WORDS THAT RHYME WITH METHOXYFLURANE


Bahrain
bɑːˈreɪn
Bahrein
bɑːˈreɪn
brain
breɪn
constrain
kənˈstreɪn
crane
kreɪn
drain
dreɪn
drivetrain
ˈdraɪvˌtreɪn
grain
ɡreɪn
Lorraine
lɒˈreɪn
membrane
ˈmɛmbreɪn
migraine
ˈmiːɡreɪn
powertrain
ˈpaʊərˌtreɪn
rain
reɪn
refrain
rɪˈfreɪn
reign
reɪn
rein
reɪn
strain
streɪn
terrain
təˈreɪn
train
treɪn
Ukraine
juːˈkreɪn

WORDS THAT BEGIN LIKE METHOXYFLURANE

methodization
methodize
methodizer
methodological
methodologically
methodologies
methodologist
methodology
methods
methomania
methotrexate
methought
methoxide
methoxy
methoxybenzene
methoxychlor
methoxyl
meths
meths drinker

WORDS THAT END LIKE METHOXYFLURANE

basilar membrane
borane
cell membrane
Coltrane
deck crane
demoiselle crane
intermembrane
mucous membrane
nictitating membrane
plasma membrane
pseudomembrane
serous membrane
subterrane
terrane
Tourane
tower crane
transmembrane
tympanic membrane
vitelline membrane
whooping crane

Synonyms and antonyms of methoxyflurane in the English dictionary of synonyms

SYNONYMS

Translation of «methoxyflurane» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF METHOXYFLURANE

Find out the translation of methoxyflurane to 25 languages with our English multilingual translator.
The translations of methoxyflurane from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «methoxyflurane» in English.

Translator English - Chinese

甲氧
1,325 millions of speakers

Translator English - Spanish

metoxiflurano
570 millions of speakers

English

methoxyflurane
510 millions of speakers

Translator English - Hindi

methoxyflurane
380 millions of speakers
ar

Translator English - Arabic

ميثوكسي فلوران
280 millions of speakers

Translator English - Russian

Метоксифлуран
278 millions of speakers

Translator English - Portuguese

methoxyflurane
270 millions of speakers

Translator English - Bengali

methoxyflurane
260 millions of speakers

Translator English - French

methoxyflurane
220 millions of speakers

Translator English - Malay

Methoxyflurane
190 millions of speakers

Translator English - German

Methoxyfluran
180 millions of speakers

Translator English - Japanese

メトキシフルラン
130 millions of speakers

Translator English - Korean

methoxyflurane
85 millions of speakers

Translator English - Javanese

Methoxyflurane
85 millions of speakers
vi

Translator English - Vietnamese

methoxyflurane
80 millions of speakers

Translator English - Tamil

methoxyflurane
75 millions of speakers

Translator English - Marathi

मॅथॉक्सी फ्लुराणे
75 millions of speakers

Translator English - Turkish

metoksifluron
70 millions of speakers

Translator English - Italian

metossifluorano
65 millions of speakers

Translator English - Polish

methoxyflurane
50 millions of speakers

Translator English - Ukrainian

метоксифлуран
40 millions of speakers

Translator English - Romanian

metoxifluranului
30 millions of speakers
el

Translator English - Greek

μεθοξυφλουράνης
15 millions of speakers
af

Translator English - Afrikaans

methoxyflurane
14 millions of speakers
sv

Translator English - Swedish

metoxifluran
10 millions of speakers
no

Translator English - Norwegian

methoxyflurane
5 millions of speakers

Trends of use of methoxyflurane

TRENDS

TENDENCIES OF USE OF THE TERM «METHOXYFLURANE»

The term «methoxyflurane» is normally little used and occupies the 130.913 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Little used
39
/100
The map shown above gives the frequency of use of the term «methoxyflurane» in the different countries.
Principal search tendencies and common uses of methoxyflurane
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «methoxyflurane».

FREQUENCY OF USE OF THE TERM «METHOXYFLURANE» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «methoxyflurane» during the past 500 years. Its implementation is based on analysing how often the term «methoxyflurane» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about methoxyflurane

EXAMPLES

10 ENGLISH BOOKS RELATING TO «METHOXYFLURANE»

Discover the use of methoxyflurane in the following bibliographical selection. Books relating to methoxyflurane and brief extracts from same to provide context of its use in English literature.
1
Small Animal Clinical Pharmacology
Pharmacokinetics Chemical and physical properties Methoxyflurane is a halogenated ether (see Fig. 5.1). It is nonflammable but unstable and so an antioxidant preservative must be included. It has an unusually low vapor pressure (see Table ...
Jill E. Maddison, Stephen W. Page, David Church (BVSc.), 2008
2
Toxicology of the Kidney
Loop of Henle/Distal Tubule/Collecting Duct Methoxyflurane The general anesthetic, methyoxyflurane, produces renal failure characterized by vasopressin -resistant polyuria and increases in serum sodium, osmolality, and BUN.
Jerry B. Hook, Robin S. Goldstein, 1993
3
Pharmacology for Anesthetists
Methoxyflurane analgesia for burns dressings and other painful ward procedures in children (subscription required)”. British Journal of Anaesthesia 44 (5): 517–22. doi: 10.1093/bja/44.5.517. PMID 5044082. 385Josephson CA, Schwartz W ...
John D. Current, M.D.
4
Medical Toxicology of Drug Abuse: Synthesized Chemicals and ...
Nephrocalcinosis may develop in patients abusing methoxyflurane.61 The most striking feature seen on renal biopsy of these patients is the deposition of birefringent crystals within tubular lumens, particularly in the cortical lumens. Thickening ...
Donald G. Barceloux, 2012
5
Hepatotoxicity: The Adverse Effects of Drugs and Other ...
Judging by the demonstrated 50% biotransformation of methoxyflurane (Table 1 7. 1 3), however, the potential for toxicity may be greater than that of halothane. The characteristics of hepatic injury associated with methoxyflurane, halothane, ...
Hyman J. Zimmerman, 1999
6
Foundations of Anesthesia: Basic Sciences for Clinical Practice
The blood solubilities of halothane, isoflurane, enflurane, and methoxyflurane are 18% less in neonates and the elderly than in young adults. These differences may be attributed to differences in blood constituents: the blood:gas partition ...
Hugh C. Hemmings, Philip M. Hopkins, 2006
7
The Effects of Scavenging on Waste Methoxyflurane ...
Veterinarians, their assistants, and animal researchers should consider the potential health hazards of chronic exposure to the inhalational anesthetic, methoxyflurane.
J. E. Milligan, J. L. Sablan, J. F. Croy, 1981
8
The Experimental Animal in Biomedical Research: Care, ...
H. ANESTHETIC GASES Methoxyflurane, halothane, enflurane, and isoflurane are inhalation anesthetics used to produce surgical anesthesia in cats. Methoxyflurane, enflurane, and isoflurane produce dose- dependent respiratory and ...
Bernard E. Rollin, 1995
9
Anesthesia and Analgesia in Laboratory Animals
D. Methoxyflurane (Metophane, Penthrane) Methoxyflurane may be administered to rodents by an open drop or induction chamber technique, although use of a calibrated vaporizer with a nonrebreathing circuit is preferable. Scavenging of ...
Dennis F. Kohn, Sally K. Wixson, William J. White, 1997
10
The Laboratory Mouse
Methoxyflurane Methoxyflurane combined with oxygen or air is the volatile agent of choice for inhalation anaesthesia in mice [3] and many investigators agreed that methoxyflurane is the safest agent to use whether by simple open-drop ...
Hans J. Hedrich, 2012

10 NEWS ITEMS WHICH INCLUDE THE TERM «METHOXYFLURANE»

Find out what the national and international press are talking about and how the term methoxyflurane is used in the context of the following news items.
1
Australia's pain relieving 'green whistle' is closing in on a $70 million …
... cost manufacturing process developed with the CSIRO to increase production of Penthrox's underlying drug methoxyflurane by ten-fold. «Business Insider Australia, Jun 15»
2
Australia's 'green whistle' invention receives green light to sell in …
The CSIRO rolled $750,000 into the production of Penthrox, and the result has been a ten-fold increase in the production of methoxyflurane. «Techly, May 15»
3
Is Medical Developments International Ltd set to post blockbuster …
Medical Developments produces a range of products and it is best known for its short-term pain management drug methoxyflurane. «Motley Fool Australia, May 15»
4
APD shares Source: TheAustralian
The Penthrox inhaler administers the drug methoxyflurane, which is considered a more palatable alternative to opioid-based relief. «The Australian, May 15»
5
Once-banned Australian pain drug to be relaunched overseas
The Penthrox inhaler administers the drug methoxyflurane for short-term pain relief. It was first used as an anaesthetic, but this was stopped in ... «The Australian, May 15»
6
Europe agrees to blow the green whistle
... Medical Developments International (ASX:MVP) team up with CSIRO to increase production of Penthrox's underlying drug, methoxyflurane, ... «Australian Life Scientist, May 15»
7
Drug Product Compounding Issues Addressed by FDA Panel
... methoxyflurane, novobiocin sodium, pemoline, pergolide mesylate, phenylpropanolamine, propoxyphene, rapacuronium bromide, rofecoxib, ... «Medscape, Feb 15»
8
Few investments beat a medical stock for price growth
It is a safe alternative to morphine, being based on the halogenated ether chemical methoxyflurane. The return from Medical Developments ... «The Australian, Feb 15»
9
Video Premiere: Bad Blocks, “Circulate”
... xray tube positioned on an angle F.ANESTHESIA methoxyflurane and enflur ane s isoflurane s desflurane and sevoflurane s.et al.Carcinoid ... «Wondering Sound, Jan 15»
10
Ambulance robbed of medical supplies while paramedics work to …
Two methoxyflurane kits for pain relief were stolen. Anyone with information is asked to phone Cabramatta Police on 9725 8999. 3 CANLEY ... «The Daily Telegraph, Dec 14»

REFERENCE
« EDUCALINGO. Methoxyflurane [online]. Available <https://educalingo.com/en/dic-en/methoxyflurane>. May 2024 ».
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