10 ENGLISH BOOKS RELATING TO «PLEIOTROPY»
Discover the use of
pleiotropy in the following bibliographical selection. Books relating to
pleiotropy and brief extracts from same to provide context of its use in English literature.
1
Release from Antagonistic
Pleiotropy and Coevolution ...
SSC1 is a gene that encodes a multifunctional mitochondrial heat shock protein that gave rise to SSQ1 by gene duplication in a subset of yeasts.
Krista Gudrais Reitenga, 2009
2
AP Biology, 2nd Ed. (Book Only)
This mutation causes the development of feathers that cannot keep the animal
warm, resulting in changes in several organ systems. Another example of
pleiotropy can be seen in Siamese cats. The allele responsible for the coloration
pattern ...
Deborah T. Goldberg, M.S.
3
Epigenetics: Linking Genotype and Phenotype in Development ...
If so, then epigenetic pleiotropy and epigenetic plasticity may cooperate in
building developmental integration into functional systems. conclusIon
Epigenetic and intrinsic genetic pleiotropy are distinct developmental
mechanisms of integration, ...
Benedikt Hallgrimsson Ph.D., Brian K. Hall Ph.D., 2011
4
The Future of Aging: Pathways to Human Life Extension
5.5.3. Adaptive. Pleiotropy: An. Alternate. Theory. Genetic tradeoffs affecting life
span appear to be a common feature across taxa, but not a precondition or
physical necessity. If we accept at face value evidence that aging itself is ...
Gregory M. Fahy, Michael D. West, L. Steven Coles, 2010
5
Variation: A Central Concept in Biology
PLEIOTROPY. The different origins of morphological covariation apply to broad
classes of variation, and in particular, they also apply to variation that results from
allelic differences that are involved in the developmental pathways. As a result ...
Benedikt Hallgrímsson, Brian K. Hall, 2011
6
Human Senescence: Evolutionary and Biocultural Perspectives
"antagonistic pleiotropy". - it did not appear in Williams' original 1957 article, nor
does he take credit for it elsewhere or recall who first used this terminology; Linda
Gerber, personal communication). At any locus, alleles that enhance survival, ...
Pleiotropy is a genetic mechanism in which a single gene produces more than
one trait. For example, wild-type D. melanogaster has smoothed, curved bristles
on its thorax, whereas the singed mutation, a single-point mutation, results in ...
8
Genetic Disorders: New Insights for the Healthcare ...
California. State. University,. Long. Beach: Antagonistic. pleiotropy. as. a.
widespread. mechanism. for. the. maintenance. of. polymorphic. disease. alleles.
“Many serious diseases have a genetic basis which, from an evolutionary point of
view, ...
9
Issues in General Science and Scientific Theory and Method: ...
(2010 JAN 19) University of Michigan, Ann Arbor: Genomic patterns of pleiotropy
and the evolution of complexity A new study, 'Genomic patterns of pleiotropy and
the evolution of complexity,' is now available. “Pleiotropy refers to the ...
10
Advances in Network Complexity
Complexity, being directly linked to restricted pleiotropy, is indeed associated
with the ability of an organism to explore the phenotypic space. With low
phenotypic complexity, all traits are affected similarly by mutations and therefore
a small ...
Matthias Dehmer, Abbe Mowshowitz, Frank Emmert-Streib, 2013
10 NEWS ITEMS WHICH INCLUDE THE TERM «PLEIOTROPY»
Find out what the national and international press are talking about and how the term
pleiotropy is used in the context of the following news items.
A robust multiple-locus method for quantitative trait locus analysis of …
... in the data may have the benefit to investigate the pleiotropy—the same gene influencing multiple traits which are (genetically) correlated. «Nature.com, Jul 15»
Are Limited Lifespans An Evolutionary Adaptation?
The second theory, called “antagonistic pleiotropy” — or the “pay later theory” — is the idea that a single gene, or characteristic, is beneficial ... «io9, Jun 15»
Several cancer susceptibility variants also affect melanoma risk
This pleiotropy-colored Manhattan plot shows the –log(10) p-value for the association between melanoma and SNPs previously associated ... «Fred Hutch News Service, May 15»
Can Scientists Turn Birds Back Into Dinosaur Ancestors?
This multi-tasking is called pleiotropy. The new experiment hints that the bird beak didn't evolve simply through a series of little steps, each ... «National Geographic, May 15»
Genetically integrated traits and rugged adaptive landscapes in …
Pleiotropy and epistasis lie at the heart of much of evolutionary theory. Together they give rise to the complex mapping between genotype and ... «BMC Blogs Network, May 15»
Theory of Convergent Evolution Analyzed
... as reflecting the dominance of natural selection plus variation over factors such as developmental constraints, pleiotropy, phylogenetic inertia ... «Discovery Institute, May 15»
GWAS in pigs confirms HMGA1 and PPARD important for height
The largest GWAS performed in beef cattle also confirmed HMGA1's pleiotropy for 'carcass traits'. The bone-length gene NCAPG identified in ... «Nature.com, May 15»
Alzheimer disease and dyslipidaemia
“Our findings indicate abundant genetic pleiotropy between AD, CRP, and plasma lipids,” says Desikan. “Many cardiovascular disease traits, ... «Nature.com, Apr 15»
Evolution - how it works
Enter pleiotropy. This is where one gene has an effect on more than one trait of a specific life form. In the case of the silver fox, the deliberate ... «News24, Apr 15»
Joint prediction of multiple quantitative traits using a Bayesian …
... were sampled from a standard bivariate normal distribution with correlation 0.5, which assumes a certain level of pleiotropy effects at all loci. «Nature.com, Apr 15»
