CHE SIGNIFICA LIGASE IN INGLESE
ligasi
Nella biochimica, la ligasi è un enzima che può catalizzare l'aggregazione di due grandi molecole formando un nuovo legame chimico, di solito con l'idrolisi associata a un piccolo gruppo chimico dipendente da una delle molecole più grandi o l'enzima che catalizza l'aggregazione di due composti, Ad esempio, enzimi che catalizzano l'adesione di CO, CS, CN, ecc. In generale, una ligasi catalizza la seguente reazione: Ab + C → A-C + b o talvolta Ab + cD → A-D + b + c dove la minuscola Le lettere significano i piccoli gruppi dipendenti. La ligasi può unire due frammenti complementari di acido nucleico e riparare interruzioni singole filo che si presentano nel DNA a doppio filamento durante la replicazione.
definizione di ligase nel dizionario inglese
La definizione di ligasi nel dizionario è una classe di enzimi che catalizzano la formazione di legami covalenti e sono importanti nella sintesi e riparazione di molecole biologiche, come il DNA.
PAROLE IN INGLESE ASSOCIATE CON «LIGASE»
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biochemistry ·
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hydrolysis ·
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ligases ·
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human ·
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phosphodiester ·
between ·
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phosphate ·
hydroxyl ·
termini ·
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kapa ·
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biosystems ·
rcsb ·
keywords ·
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biotechnology ·
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engineering ·
recombinant ·
technology ·
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life ·
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ligation ·
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other ·
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class ·
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10 LIBRI IN INGLESE ASSOCIATI CON «LIGASE»
Scopri l'uso di
ligase nella seguente selezione bibliografica. Libri associati con
ligase e piccoli estratti per contestualizzare il loro uso nella letteratura.
1
Nucleic Acid Amplification Technologies: Application to ...
This book is designed for all biomedical scientists interested in the application of molecular biology to clinical diagnosis."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
Helen H. Lee, Stephen A. Morse, Ørjan Olsvik,
1997
2
Enzymology Primer for Recombinant DNA Technology
RNA LIGASE: T4 RNA LIGASE [Polyribonucleotide synthase (ATP), EC 6.5.1.3]
RNA ligases catalyze the 3' — > 5' phosphodiester bond formation of RNA
molecules with concomitant hydrolysis of ATP to AMP and PP; . Initially detected
as an ...
3
Base Excision Repair of DNA Damage
replication, at least during early embryogen- esis.46 Studies on DNA replication
and DNA repair in cell lines established from these DNA ligase I mutant embryos
should prove informative. DNA LIGASE II PHYSICAL AND BIOCHEMICAL ...
This was readily demonstrated in the first step, the formation of ligase-adenylate,
but was technically difficult to prove in the next two steps, the formation and
consumption of DNA-adenylate. An interesting kinetic feature is the activation of
E.
Arthur Kornberg, Tania A. Baker,
2005
5
RNA-Protein Interactions : A Practical Approach: A Practical ...
ligase' reflected this ability (29, 30). Like T4 RNA ligase, T4 DNA ligase joins the
3' OH of a 5' acceptor polynucleotide to a 5' terminal monophosphate of a 3'
donor polynucleotide in the presence of ATP. However, unlike T4 RNA ligase, ...
Christopher W.J. Smith,
1998
6
A Laboratory Guide to RNA: Isolation, Analysis, and Synthesis
Isolation, Analysis, and Synthesis Paul A. Krieg. merase I, and RNase H, and E.
coli DNA ligase. The conditions and enzyme concentrations for second-strand
cDNA synthesis have been optimized to produce high yields of double-stranded
...
7
Molecular Biology: A Project Approach
Ligase, an enzyme that uses ATP to form bonds, is used in recombinant DNA
cloning to join restriction endonuclease fragments that have annealed. The
ligase commonly used is T4 DNA ligase, which was first isolated from E. coJi that
were ...
8
Recombinant DNA Principles and Methodologies
The ligase has a relatively low turnover number of 25 sealing events per minute
per ligase molecule. The polyionic polymer PEG 8000 greatly enhances the rate
of phosphodiester bond formation by ligase, presumably by increasing the local ...
9
Proteomics of Spermatogenesis
multi-cellular eukaryotes contain more than one species of DNA ligase. DNA
ligase I is required for DNA replication involved in DNA repair. Pol-[5 and DNA
ligase-l seem to be components of a multi-protein complex that performs base ...
10
Experimental Techniques in Bacterial Genetics
co/i and S. typhimurium have an NAD dependent DNA ligase that is essential for
repairing nicks generated during DNA replication and recombination in vivo . The
DNA ligase commonly u sed for DNA cloning is made by phage T4. In contrast ...
10 NOTIZIE DOVE SI INCLUDE IL TERMINE «LIGASE»
Vedi di che si parla nei media nazionali e internazionali e come viene utilizzato il termine ino
ligase nel contesto delle seguenti notizie.
Spectrum and frequencies of BRCA1/2 mutations in Bulgarian high …
... in the RING domain and abolished the ubiquitin ligase activity of BRCA1 protein as well as its participation in the homologous recombination ... «BMC Blogs Network, lug 15»
Genome-wide gene–gene interaction analysis for next-generation …
Article | PubMed |; Emanuele MJ, Elia AE, Xu Q et al: Global identification of modular cullin-RING ligase substrates. Cell 2011; 147: 459–474. «Nature.com, lug 15»
Digestion of Nucleic Acids Starts in the Stomach
3c). As shown in Fig. 3c, if a fragment has a 3′-phosphate, its 3′ end will not be ligated to another synthesized oligo-DNA by T4 DNA ligase, ... «Nature.com, lug 15»
Surveying the repair of ancient DNA from bones via high-throughput …
Both methods use endonucleases and glycosylases along with a DNA polymerase-ligase combination. PreCR Repair Mix increases the number of molecules ... «BioTechniques.com, lug 15»
WesternU Researchers Unveil New Mechanism in the Regulation of …
This study shows that a type of SK, the synaptic SK2 channels, are regulated by the E3 ubiquitin ligase UBE3A, whose deficiency results in ... «Benzinga, lug 15»
Not All Dengue Viruses Have Have Same Potential For Disease …
This subgenomic RNA then binds a host protein, TRIM25, which is a E3 ubiquitin ligase that polyubiquitylates RIG-I to amplify and sustain ... «Medical Research News and Interviews on MedicalResearch.com, lug 15»
The proinflammatory role of HECTD2 in innate immunity and …
We discovered a ubiquitin E3 ligase, HECTD2, which ubiquitinated and mediated the degradation of PIAS1, thus increasing inflammation in an experimental ... «Science Magazine, lug 15»
A nonsense variant in HERC1 is associated with intellectual …
HERC1 is an ubiquitin ligase that interacts with tuberous sclerosis complex 2, an upstream negative regulator of the mTOR pathway. Our data ... «Nature.com, lug 15»
Promotion of Endoplasmic Reticulum-Associated Degradation of …
Depletion of particular ERAD-associated isomerases, lectins, and translocon components, including ERAD E3 ubiquitin ligase HRD1, ... «Journal of Virology, lug 15»
Hybrid vigour: Infertility rescue
The male sterility thus induced is rescued in hybrids because TBPm3 is tagged with an additional protein fragment used by the ubiquitin ligase, ... «Nature.com, lug 15»