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Meaning of "macroglobulin" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF MACROGLOBULIN

macroglobulin  [ˌmækrəʊˈɡlɒbjʊlɪn] play
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GRAMMATICAL CATEGORY OF MACROGLOBULIN

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Macroglobulin is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES MACROGLOBULIN MEAN IN ENGLISH?

Macroglobulin

A macroglobulin is a plasma globulin of high molecular weight. Elevated levels of macroglobulins may cause manifestations of excess blood viscosity and/or precipitate within blood vessels when temperature drops. Other macroglobulins include alpha-2 macroglobulin, which is elevated in nephrotic syndrome, diabetes, severe burns, and other conditions, while a deficiency is associated with chronic obstructive pulmonary disease.

Definition of macroglobulin in the English dictionary

The definition of macroglobulin in the dictionary is an immunoglobulin of unusually high relative molecular mass, observed in the blood in some diseases. Other definition of macroglobulin is Also called: immunoglobulin M. the normal form of this immunoglobulin.

WORDS THAT RHYME WITH MACROGLOBULIN


aesculin
ˈiːskjʊlɪn
antiglobulin
ˌæntɪˈɡlɒbjʊlɪn
botulin
ˈbɒtjʊlɪn
calmodulin
kəlˈmɒdjʊlɪn
cryoglobulin
ˌkraɪəʊˈɡlɒbjʊlɪn
euglobulin
juːˈɡlɒbjʊlɪn
globulin
ˈɡlɒbjʊlɪn
hypermasculine
ˌhaɪpəˈmæskjʊlɪn
immunoglobulin
ˌɪmjʊnəʊˈɡlɒbjʊlɪn
insulin
ˈɪnsjʊlɪn
inulin
ˈɪnjʊlɪn
lactoglobulin
ˌlæktəʊˈɡlɒbjʊlɪn
levulin
ˈlɛvjʊlɪn
lupulin
ˈluːpjʊlɪn
masculine
ˈmæskjʊlɪn
proinsulin
prəʊˈɪnsjʊlɪn
thyroglobulin
ˌθaɪrəʊˈɡlɒbjʊlɪn
tuberculin
tjʊˈbɜːkjʊlɪn
tubulin
ˈtjuːbjʊlɪn
unmasculine
ʌnˈmæskjʊlɪn

WORDS THAT BEGIN LIKE MACROGLOBULIN

macrodont
macroeconomic
macroeconomics
macroevolution
macroevolutionary
macrofauna
macroflora
macrofossil
macrogamete
macroglia
macrograph
macrographic
macrolepidoptera
macrolinguistics
macrology
macromarketing
macromere
macromole
macromolecular
macromolecule

WORDS THAT END LIKE MACROGLOBULIN

beta globulin
folliculin
gamma globulin
indulin
laevulin
moulin
patulin
paulin
serum globulin
tarpaulin
torulin

Synonyms and antonyms of macroglobulin in the English dictionary of synonyms

SYNONYMS

Translation of «macroglobulin» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF MACROGLOBULIN

Find out the translation of macroglobulin to 25 languages with our English multilingual translator.
The translations of macroglobulin from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «macroglobulin» in English.

Translator English - Chinese

巨球蛋白
1,325 millions of speakers

Translator English - Spanish

macroglobulina
570 millions of speakers

English

macroglobulin
510 millions of speakers

Translator English - Hindi

macroglobulin
380 millions of speakers
ar

Translator English - Arabic

ماكروغلوبولين
280 millions of speakers

Translator English - Russian

макроглобулин
278 millions of speakers

Translator English - Portuguese

macroglobulina
270 millions of speakers

Translator English - Bengali

macroglobulin
260 millions of speakers

Translator English - French

macroglobuline
220 millions of speakers

Translator English - Malay

Makroglobulin
190 millions of speakers

Translator English - German

Makroglobulin
180 millions of speakers

Translator English - Japanese

マクログロブリン
130 millions of speakers

Translator English - Korean

마크로 글로불린
85 millions of speakers

Translator English - Javanese

Macroglobulin
85 millions of speakers
vi

Translator English - Vietnamese

macroglobulin
80 millions of speakers

Translator English - Tamil

macroglobulin
75 millions of speakers

Translator English - Marathi

मॅक्रोोग्लोबुलिन
75 millions of speakers

Translator English - Turkish

makroglobulin
70 millions of speakers

Translator English - Italian

macroglobulina
65 millions of speakers

Translator English - Polish

makroglobulina
50 millions of speakers

Translator English - Ukrainian

макроглобулин
40 millions of speakers

Translator English - Romanian

macroglobulin
30 millions of speakers
el

Translator English - Greek

μακρογλοβουλίνη
15 millions of speakers
af

Translator English - Afrikaans

macroglobulin
14 millions of speakers
sv

Translator English - Swedish

makroglobulin
10 millions of speakers
no

Translator English - Norwegian

makroglobulin
5 millions of speakers

Trends of use of macroglobulin

TRENDS

TENDENCIES OF USE OF THE TERM «MACROGLOBULIN»

The term «macroglobulin» is regularly used and occupies the 104.174 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
52
/100
The map shown above gives the frequency of use of the term «macroglobulin» in the different countries.
Principal search tendencies and common uses of macroglobulin
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «macroglobulin».

FREQUENCY OF USE OF THE TERM «MACROGLOBULIN» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «macroglobulin» during the past 500 years. Its implementation is based on analysing how often the term «macroglobulin» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about macroglobulin

EXAMPLES

10 ENGLISH BOOKS RELATING TO «MACROGLOBULIN»

Discover the use of macroglobulin in the following bibliographical selection. Books relating to macroglobulin and brief extracts from same to provide context of its use in English literature.
1
Wintrobe's Clinical Hematology
c*2-Macroglobulin is a nonspecific proteinase inhibitor that targets a broad spectrum of protease substrates. It is present in human plasma at concentrations ranging from 2 to 4 /xmol/L (2 to 3 mg/ml) (Table 20.4). <*2-Macroglobulin can also be ...
John P. Greer, 2009
2
Protein Electrophoresis in Clinical Diagnosis
a2-Macroglobulin is one of the two major proteins in the a2-region. Synthesized mainly by the liver, it is a tetramer composed of four identical subunits. The subunits are held together as dimers by disulfide bonds. Each a2-macroglobulin  ...
David Keren, 2003
3
Biology of Antithrombins
Keinman, R. D., Yuan, A. I., Winder, A. R., and Wang, D., Kinetics of the reaction of thrombin and a2-macroglobulin, Biochem. J., 231, 417, 1985. 69. Duke Virca, G. and Travis, J., Kinetics of association of human proteinases with human a ...
Geza Sas, 1989
4
Clinical Applications of TGF-
I thought it would all be consumed by a2~macroglobulin, nevertheless there is potent immunosuppression in vivo. How can we explain such findings? LaMarre: We have been looking at the effect of different modified forms of oQ- macroglobulin ...
CIBA Foundation Symposium, 2008
5
Acute Phase Proteins Molecular Biology, Biochemistry, and ...
Strickland, D. K., Larsson, L. J., Neuenschwander, D. E., and Bjork, I., Reaction of proteinases with alpha-2-macroglobulin. Rapid kinetic evidence for a conformational rearrangement of the initial alpha-2- macroglobulin-trypsin complex, ...
Andrzej Mackiewicz, Irving Kushner, Heinz Baumann, 1993
6
Hyperthermia In Cancer Treatment: A Primer: A Primer
Immunology 1986; 57(3):367-71. 727. Wollenberg GK, LaMarre J, Rosendal S et al. Binding of tumor necrosis factor alpha to activated forms of human plasma alpha 2 macroglobulin. Am J Pathol 1991a; 138(2):265-72. 728. O'Connor- McCourt ...
Gian F. Baronzio, E. Dieter Hager, 2008
7
Blood Coagulation
R.F.A. Zwaal, H.C. Hemker. cleavage of a vulnerable region near the middle of the a2-macroglobulin subunit chain, followed by a conformational change resulting in steric entrapment of the enzyme [159]. The active site of the bound protease ...
R.F.A. Zwaal, H.C. Hemker, 1986
8
Neuroinflammatory Mechanisms in Alzheimer's Disease: Basic ...
21 LaMarre J, Wollenberg GK, Gonias SL, Hayes AM (1991) Cytokine binding and clearance properties of proteinase-activated a2-macroglobulin. Lab Invest 65: 3-14 22 Chu CT, Howard GC, Misra UK, Pizzo SV (1994) a2-Macroglobulin: a  ...
Joseph Rogers, 2001
9
Immunosenescence
Lysiak JJ, Hussaini IM, Gonias SL. alpha 2-Macroglobulin synthesis by the human monocytic cell line THP-1 is differentiation state-dependent. J Cell Biochem 1997; 67:492-497. 33. Heumann D, Vischer TL. Immunomodulation by alpha ...
Graham Pawelec, 2008
10
Cell and Molecular Biology of the Testis
The synthesis and secretion of a2-macroglob- ulin by cultured Sertoli cells was confirmed by immunoprecipitation and radioimmunoassay. To obtain evidence for the presence of testicular a2-macroglobulin in the adluminal compartment of the ...
Claude Desjardins, Larry L. Ewing, 1993

10 NEWS ITEMS WHICH INCLUDE THE TERM «MACROGLOBULIN»

Find out what the national and international press are talking about and how the term macroglobulin is used in the context of the following news items.
1
Why Do Dilute Bleach Baths Improve Atopic Dermatitis?
Interestingly, for the first time to our knowledge, α-2 macroglobulin, a ubiquitous protein found in the skin that binds a host of proteases, growth ... «Medical Research News and Interviews on MedicalResearch.com, Jul 15»
2
Development of a blood-based molecular biomarker test for …
... inflammation (alpha-2 macroglobulin (A2M), beta-2 microglobulin (B2M), carcinoembryonic antigen (CA), haptoglobin, interleukin-1 receptor ... «Nature.com, Jul 15»
3
Rare gene variant associated with middle ear infections
Another gene called alpha 2-macroglobulin or A2M, which encodes a protein that is found at high levels in very infected ears, is formed in such ... «Baylor College of Medicine News, Jun 15»
4
Galectin Therapeutics (GALT) Commences GR-MD-02 Phase 2 in …
... on fibrosis as shown by reduced serum alpha-2 macroglobulin, a marker of fibrosis, and reduced liver stiffness as assessed by FibroScan®. «StreetInsider.com, Jun 15»
5
Cytonics Starts FDA Arthritis Trial, Enrolling First Patient in A2M …
The APIC-CF System concentrates the protease inhibitor Alpha-2-Macroglobulin (A2M) from a patient's own blood for direct injection into a joint ... «Digital Journal, Jun 15»
6
Thinking Inside The Box: Insights Into One Of The World's Deadliest …
... four of which were metalloproteinases, an alpha-macroglobulin domain containing protein, two peroxiredoxin toxins, two CRISP proteins and ... «Discover Magazine, Jun 15»
7
Get a celiac test before giving up gluten
We found those who eat the most gluten experience a rise in blood levels of alpha-2 macroglobulin, which indicates inflammation and also is a ... «Toronto Star, Apr 15»
8
Prostate cancer New ligand–receptor targets
Using affinity chromatography, Mandelin et al. identified α2-macroglobulin as the receptor for PKRGFQD and GRP78 as the receptor for ... «Nature.com, Mar 15»
9
Ibrutinib Approved in US for Rare Lymphoma
These abnormal B-cells also overproduce a protein known as immunoglobulin M or IgM (macroglobulin) that may lead to excess bleeding and ... «Medscape, Jan 15»
10
Final Phase 1 Trial Results Demonstrate Galectin Therapeutics' GR …
The decrease in FibroTest® score was attributable to a marked, statistically significant reduction in serum alpha-2 macroglobulin (A2M), ... «GlobeNewswire, Jan 15»

REFERENCE
« EDUCALINGO. Macroglobulin [online]. Available <https://educalingo.com/en/dic-en/macroglobulin>. May 2024 ».
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