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Meaning of "holoenzyme" in the English dictionary

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DICTIONARY
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PRONUNCIATION OF HOLOENZYME

holoenzyme  [ˌhɒləʊˈɛnzaɪm] play
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GRAMMATICAL CATEGORY OF HOLOENZYME

noun
adjective
verb
adverb
pronoun
preposition
conjunction
determiner
exclamation
Holoenzyme is a noun.
A noun is a type of word the meaning of which determines reality. Nouns provide the names for all things: people, objects, sensations, feelings, etc.

WHAT DOES HOLOENZYME MEAN IN ENGLISH?

Enzyme

Enzymes /ˈɛnzaɪmz/ are large biological molecules responsible for the thousands of metabolic processes that sustain life. They are highly selective catalysts, greatly accelerating both the rate and specificity of metabolic reactions, from the digestion of food to the synthesis of DNA. Most enzymes are proteins, although some catalytic RNA molecules have been identified. Enzymes adopt a specific three-dimensional structure, and may employ organic and inorganic cofactors to assist in catalysis. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates sufficient for life. Since enzymes are selective for their substrates and speed up only a few reactions from among many possibilities, the set of enzymes made in a cell determines which metabolic pathways occur in that cell. Like all catalysts, enzymes work by lowering the activation energy for a reaction, thus dramatically increasing the rate of the reaction.

Definition of holoenzyme in the English dictionary

The definition of holoenzyme in the dictionary is an active enzyme consisting of a protein component and its coenzyme.

WORDS THAT RHYME WITH HOLOENZYME


allozyme
ˈæləʊˌzaɪm
apoenzyme
ˌæpəʊˈɛnzaɪm
azyme
ˈæzaɪm
coenzyme
kəʊˈɛnzaɪm
ectoenzyme
ˌɛktəʊˈɛnzaɪm
endoenzyme
ˌɛndəʊˈɛnzaɪm
enzyme
ˈɛnzaɪm
exoenzyme
ˌɛksəʊˈɛnzaɪm
isoenzyme
ˌaɪsəʊˈɛnzaɪm
isozyme
ˈaɪsəʊˌzaɪm
lysozyme
ˈlaɪsəˌzaɪm
multienzyme
ˌmʌltɪˈenzaɪm
proenzyme
prəʊˈɛnzaɪm
ribozyme
ˈraɪbəʊˌzaɪm
zyme
zaɪm

WORDS THAT BEGIN LIKE HOLOENZYME

holoblastic
holoblastically
Holocaine
holocaust
holocaustal
holocaustic
Holocene
holocrine
holocrystalline
Holodiscus
Holofernes
hologamy
hologram
holograph
holographer
holographic
holographically
holography
hologynic
hologyny

WORDS THAT END LIKE HOLOENZYME

basil-thyme
berhyme
chyme
cyme
eye rhyme
feminine rhyme
half-rhyme
internal rhyme
isocryme
mesenchyme
near rhyme
Newcastle-under-Lyme
nursery rhyme
perfect rhyme
restriction enzyme
rhyme
rich rhyme
slant rhyme
styme
thyme

Synonyms and antonyms of holoenzyme in the English dictionary of synonyms

SYNONYMS

Translation of «holoenzyme» into 25 languages

TRANSLATOR
online translator

TRANSLATION OF HOLOENZYME

Find out the translation of holoenzyme to 25 languages with our English multilingual translator.
The translations of holoenzyme from English to other languages presented in this section have been obtained through automatic statistical translation; where the essential translation unit is the word «holoenzyme» in English.

Translator English - Chinese

全酶
1,325 millions of speakers

Translator English - Spanish

holoenzima
570 millions of speakers

English

holoenzyme
510 millions of speakers

Translator English - Hindi

holoenzyme
380 millions of speakers
ar

Translator English - Arabic

عميم الإنزيم
280 millions of speakers

Translator English - Russian

холофермента
278 millions of speakers

Translator English - Portuguese

holoenzyme
270 millions of speakers

Translator English - Bengali

holoenzyme
260 millions of speakers

Translator English - French

holoenzyme
220 millions of speakers

Translator English - Malay

Holoenzyme
190 millions of speakers

Translator English - German

Holoenzym
180 millions of speakers

Translator English - Japanese

ホロ酵素
130 millions of speakers

Translator English - Korean

holoenzyme
85 millions of speakers

Translator English - Javanese

Holoenzyme
85 millions of speakers
vi

Translator English - Vietnamese

holoenzyme
80 millions of speakers

Translator English - Tamil

முழுஎன்சைம்
75 millions of speakers

Translator English - Marathi

होलोजनोइम
75 millions of speakers

Translator English - Turkish

holoenzyme
70 millions of speakers

Translator English - Italian

oloenzima
65 millions of speakers

Translator English - Polish

holoenzymu
50 millions of speakers

Translator English - Ukrainian

холофермента
40 millions of speakers

Translator English - Romanian

holoenzimatic
30 millions of speakers
el

Translator English - Greek

ολοένζυμο
15 millions of speakers
af

Translator English - Afrikaans

holoenzyme
14 millions of speakers
sv

Translator English - Swedish

holoenzym
10 millions of speakers
no

Translator English - Norwegian

holoenzyme
5 millions of speakers

Trends of use of holoenzyme

TRENDS

TENDENCIES OF USE OF THE TERM «HOLOENZYME»

The term «holoenzyme» is regularly used and occupies the 105.855 position in our list of most widely used terms in the English dictionary.
0
100%
FREQUENCY
Regularly used
51
/100
The map shown above gives the frequency of use of the term «holoenzyme» in the different countries.
Principal search tendencies and common uses of holoenzyme
List of principal searches undertaken by users to access our English online dictionary and most widely used expressions with the word «holoenzyme».

FREQUENCY OF USE OF THE TERM «HOLOENZYME» OVER TIME

The graph expresses the annual evolution of the frequency of use of the word «holoenzyme» during the past 500 years. Its implementation is based on analysing how often the term «holoenzyme» appears in digitalised printed sources in English between the year 1500 and the present day.

Examples of use in the English literature, quotes and news about holoenzyme

EXAMPLES

10 ENGLISH BOOKS RELATING TO «HOLOENZYME»

Discover the use of holoenzyme in the following bibliographical selection. Books relating to holoenzyme and brief extracts from same to provide context of its use in English literature.
1
Eukaryotic Nucleus
The pol III holoenzyme has been purified and resolved into its subunit structure and the function of many of the subunits have now been defined (McHenry, 1988; Kornberg, 1988; 1982; 1980). The holoenzyme, with a molecular mass of about ...
Samuel H. Wilson, 1990
2
Molecular Biology: Genes to Proteins
Written for the undergraduate and first year graduate students within molecular biology or molecular genetics, the text has been updated with the latest data in the field.
Burton E. Tropp, 2012
3
Links Between Recombination and Replication: Vital Roles of ...
Gp43 binds to this complex to generate the holoenzyme in which gp45 acts to topologically link gp43 to DNA, effectively increasing the processivity of DNA replication. Stopped-flow fluorescence resonance energy transfer was used to ...
Proceedings of the National Academy of Sciences, 2002
4
Kinetic Characterization of GreB Binding to RNA Polymerase ...
I performed preliminary gel densitometry analysis (data not shown) that confirm the formation of stable open complexes by a significant fraction of the holoenzyme molecules, in the presence of all the above three scaffolds. GreB binding to ...
Harini Ravi, 2008
5
RNA Polymerase and Associated Factors
2A [data for RNAP holoenzyme derivative labeled at 70 residue 569, within 70 region 4, and DNA fragment lacUV511 (Cy5, À40)]. Upon addition of the NTP subset that permits formation of an RNA product of 11 nt and incubation for 10 min, ...
Sankar Adhya, Susan Garges, 2003
6
DNA Replication
178 5-5 DNA Polymerase III Holoenzyme of E. co/i: ATP Activation f. co/i Pol I Other Than CHAPTER 5: Prokaryotic dna The high processivity of pol III holoenzyme, the feature that distinguishes it from its subassemblies (pol III, pol III' , and pol ...
Arthur Kornberg, Tania A. Baker, 2005
7
The Enzymes
Most purification procedures give RNA polymerase fractions that contain both core polymerase and RNA polymerase holoenzyme; that is, sigma is not present in stoichiometric amounts. Furthermore, it is now clear that, at least in B. subtilis, ...
Paul D. Boyer, 1982
8
Proteomics for Biological Discovery
In order to examine the active form of this enzyme, σ70 from recombinant sources was added to core enzyme in a 1:1 ratio to reconstitute the holoenzyme. Figure 8.5B shows a spectrum recorded for this solution. By comparison with the core ...
Timothy D. Veenstra, John R. Yates, 2006
9
Protein Kinase CK2 — From Structure to Regulation: From ...
Recombinant human holoenzyme and chimeric CK2 were challenged with increasing amounts of urea starting from 0.4-4 M urea. Figure 4A shows the effect of the various urea concentrations on the activity of the two enzymes. In the case of ...
Khalil Ahmed, J.E. Allende, Olaf-Georg Issinger, 2002
10
Cyclic-Amp-Dependent Protein Kinase
Preincubation of holoenzyme with cyclic AMP prior to ultracentrifugation result; in the formation of the 4.1 S species (Fig. 7E> characteristic of the catalytic subunit » s.i derived from each species of holoenzyme (Krebs. 1972 1. If holoenzyme is ...
Randall Murray, 1977

10 NEWS ITEMS WHICH INCLUDE THE TERM «HOLOENZYME»

Find out what the national and international press are talking about and how the term holoenzyme is used in the context of the following news items.
1
Restricted Protein Phosphatase 2A Targeting by Merkel Cell …
MCV sT has a restricted range for PP2A B subunit substitution, inhibiting only the assembly of B56α into the phosphatase holoenzyme. «Journal of Virology, Mar 15»
2
Study Finds TERT Mutations Could Predict Survival Outcome in …
... the promoter region of the TERT (telomerase reverse transcriptase) gene, which encodes the catalytic subunit of the telomerase holoenzyme. «Melanoma News Today, Dec 14»
3
Flip the Telomerase On/Off Switch to Slow Aging
“The balance between the assembly and disassembly pathways, which dictate the levels of the active holoenzyme in the cell, reveals a novel ... «Genetic Engineering & Biotechnology News, Sep 14»
4
Honing In On The Fountain Of Youth: A Deeper Understanding Of …
Chen continues that, "Despite the strong medical applications, the mechanism for telomerase holoenzyme (the most important unit of the ... «Medical Daily, May 14»
5
Improved Native Isolation of Endogenous Protein A-Tagged Protein …
... pentameric GINS complex) and bacteria (RNAP holoenzyme). The majority of the affinity-isolated material is released within 15 minutes under mild conditions, ... «BioTechniques.com, Apr 13»
6
Crucial step in human DNA replication observed for the first time
Subsequently, the clamp loader dissociated from DNA. "Our research demonstrates that the DNA polymerase holoenzyme in humans consists ... «Phys.Org, Apr 13»
7
Two of the World's Leading Experts on Bacterial Flagellar Assembly …
... the latter codes for the anti-sigma factor FlgM, which prohibits σ28 from interacting with the RNA polymerase holoenzyme complex (Saini et ... «Discovery Institute, Mar 13»
8
Continuous enzyme-coupled assay of phosphate- or pyrophosphate …
Crude E. coli DNA polymerase III holoenzyme was prepared as previously described (13). Determination of phosphate with Malachite green. The procedure ... «BioTechniques.com, Aug 12»
9
Cooperation between p53 and the telomere-protecting shelterin …
... subunit of the telomerase holoenzyme (Telomerase RNA Component, or TERC). In contrast, Pot1a inactivation results in telomere elongation ... «Nature.com, Jun 12»
10
New BRCA1-Associated Breast Cancer Susceptibility Gene Identified
The mutant protein did, moreover, retain its interaction with BRCA1 and other components of the holoenzyme complex in the cytoplasm, while ... «Genetic Engineering News, Feb 12»

REFERENCE
« EDUCALINGO. Holoenzyme [online]. Available <https://educalingo.com/en/dic-en/holoenzyme>. May 2024 ».
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