10 PORTUGUESE BOOKS RELATING TO «LIGASE»
Discover the use of
ligase in the following bibliographical selection. Books relating to
ligase and brief extracts from same to provide context of its use in Portuguese literature.
Uses The T4 DNA ligase is used to ligate DNA fragments with either 50- or 30-
protruding or blunt ends. This enzyme is the only DNA ligase known that can
catalyze blunt-end joining [1852]. An important use of T4 DNA ligase is the
preparation ...
2
Gender and Glutamate Cysteine
Ligase Modifier Subunit ...
Glutathione (GSH) is an endogenous tripeptide that protects cells against oxidative injury and is an important co-factor in drug and xenobiotic metabolism.
3
Regulation of the Rsp5 HECT Domain Ubiquitin
Ligase
The results of these studies help contribute to our understanding of the mechanisms that regulate the activity of Rsp5 and related ubiquitin ligases.
4
Base Excision Repair of DNA Damage
replication, at least during early embryogen- esis.46 Studies on DNA replication
and DNA repair in cell lines established from these DNA ligase I mutant embryos
should prove informative. DNA LIGASE II PHYSICAL AND BIOCHEMICAL ...
5
Regulation of FOXO Stability and Activity by MDM2 E3
Ligase
Members of the forkhead class O (FOXO) transcription factors are tumor suppressors and key molecules that control aging and lifespan.
This was readily demonstrated in the first step, the formation of ligase-adenylate,
but was technically difficult to prove in the next two steps, the formation and
consumption of DNA-adenylate. An interesting kinetic feature is the activation of
E.
Arthur Kornberg, Tania A. Baker,
2005
7
Continuous in Vitro Evolution of Competing
Ligase Ribozymes
Continuous evolution is the most efficient and powerful method for evolving
functional molecules in vitro, but thus far has only been applied to descendants of
the class I ligase. It has been hypothesized that continuous evolution could be
used ...
8
Proteomics of Spermatogenesis
multi-cellular eukaryotes contain more than one species of DNA ligase. DNA
ligase I is required for DNA replication involved in DNA repair. Pol-[5 and DNA
ligase-l seem to be components of a multi-protein complex that performs base ...
9
PROG NUCLEIC ACID RES&MOLECULAR BIO
The participation of ligase in replication has also been questioned, and even the
observation of nascent DNA fragments has been ascribed to a form of artifact
secondary to the metabolic effects of thymidine (108). Some comments can be ...
James Norman Davidson, Waldo E. Cohn,
1972
10
Enzymology Primer for Recombinant DNA Technology
iii. Cofactor requirements (a) NAD. The £. coli DNA ligase shows a highly specific
cofactor requirement for NAD (2,6). The equilibrium for the reaction (ligase + ATP
^ ligase- AMP + PPJ lies 28 times in favor of the formation of the ligase- AMP.
10 NEWS ITEMS WHICH INCLUDE THE TERM «LIGASE»
Find out what the national and international press are talking about and how the term
ligase is used in the context of the following news items.
Genome-wide RNAi screening implicates the E3 ubiquitin ligase …
Genome-wide RNAi screening implicates the E3 ubiquitin ligase Sherpa in mediating innate immune signaling by Toll in Drosophila adults. Hirotaka Kanoh,*,† ... «Science Magazine, Oct 15»
Nanobody-targeted E3-ubiquitin ligase complex degrades nuclear …
Ab-SPOP ligase, but not Abmutation-SPOP (in which the GFP-recognition domain of the vhhGFP4 nanobody was deleted), degraded all six GFP fusion proteins ... «Nature.com, Sep 15»
The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated …
The E3 ubiquitin ligase RNF43 inhibits Wnt–β-catenin signaling. Rather than promoting the degradation of cell surface Wnt receptors, Loregger et al. found that ... «Science Magazine, Sep 15»
Sensitizing melanoma to chemotherapeutic drugs
APC/C is an E3 ubiquitin ligase complex that coordinates aspects of the cell cycle by targeting cell cycle regulators, such as cyclins, for destruction. Cao et al. «Science Magazine, Sep 15»
Proteomic analysis reveals an inhibitor
By mediating the attachment of ubiquitin chains, E3 ubiquitin ligases stimulate the internalization and degradation, and hence reduce the activity, of various ... «Science Magazine, Apr 15»
Comparative analysis of T4 DNA ligases and DNA polymerases …
This method relies on enzymatic cleavage of cross-linked chromatin and consecutive ligation to create ligation junctions between physically adjacent loci, ... «BioTechniques.com, Apr 15»
Molecular Biology Enzymes, Kits, & Reagents Market by Application …
The enzymes segment is divided into the ligases, phosphatases, polymerases, ... The ligase enzyme sub-segment is further divided into T4 DNA ligase, ... «MarketWatch, Aug 14»
Market for Molecular Biology Reagents, Enzymes & Kits Analyzed …
Molecular Biology Enzymes, Kits, & Reagents Market by Application (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing), Product (Ligase, ... «PR Newswire, Aug 14»
Cell resiliency surprises scientists
These tools are a family of proteins called DNA Ligases, which are needed for a variety of processes associated with DNA. There are several forms of these ... «MSUToday, Apr 14»
DNA sequencing part 2: ligases and PCR
Although the approaches they take are quite different, all of them rely on some combination of two key biochemical reactions: DNA ligation, and Polymerase ... «Ars Technica, Nov 09»