CĂRȚI ÎN ENGLEZĂ ÎN LEGĂTURĂ CU «CHELATABLE»
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1
The Liver: Biology and Pathobiology
Chelatable iron is an emerging dynamic regulator of cellular function and
mediator of cytotoxicity. Like free Ca2+, chelatable iron may represent both a
signal-regulating normal cellular response and an intracellular mediator of
toxicity when ...
Irwin Arias, Allan Wolkoff, James Boyer,
2011
2
Industrial Chemical Exposure: Guidelines for Biological ...
(1995), PbB was found to be an important predictor of EDTA-chelatable lead,
whereas 5-aminolevulinic acid in urine (ALAU) was associated with DMSA-
chelatable lead. The association of ALAU with DMSA-chelatable lead is
consistent with ...
Robert R. Lauwerys, Perrine Hoet,
2001
3
Air Quality Criteria for Lead
One consequence of this relationship is that moderately elevated blood lead
values will tend to mask the “margin of safety" in terms of mobile body lead
burdens. Such masking is apparent in several studies of children where
chelatable lead ...
4
Iron Physiology and Pathophysiology in Humans
The small magnitude of the rapidly chelatable iron fraction also impacts the
dosing strategy for chelation therapy. By increasing the dose of chelators in an
attempt to accelerate iron removal from tissues, there is an increasing risk of
toxicity ...
Gregory J. Anderson, Gordon D. McLaren,
2012
5
Lead and Public Health: Science, Risk and Regulation
Chelatable Pb does not define metabolic and anatomically distinct sites in the
manner that Pb in soft and mineralizing sites does. The term is chiefly
characterized biokinetically within regimens using different chelants and different
chelants ...
6
Textbook of Interventional Cardiovascular Pharmacology
The majority of body iron is not chelatable (iron from cytochromes and
hemoglobin). There are two major pools of chelatable iron by DFO (19). The first
is that delivered from the breakdown of red cells by macrophages. DFO competes
with ...
Nicolas Kipshidze, Jawad Fareed, Patrick W. Serruys,
2007
7
Biologic Markers in Reproductive Toxicology
Chelatable Lead The most critical measure of exposure is the amount of lead
available to general circulation—also known as the chelatable-lead pool. The
amount of chelatable lead in children is determined by administering a calculated
...
Subcommittee on Reproductive and Neurodevelopmental Toxicology, Committee on Biologic Markers, Board on Environmental Studies and Toxicology,
1989
8
Handbook of the Behavioral Neurobiology of Serotonin
Fe3 may be a minor component of the chelatable iron pool owing to the great
capacity of cytosolic ferritin to bind under physiological conditions. Hence, Fe3
might not be competitive with Fe2 in the cell, although TPH is very sensitive to
added ...
Christian P. Muller, Barry Jacobs,
2009
9
Drug-Induced Liver Disease
Nonchelatable iron is inaccessible to iron chelators like desferal and resides in
ferritin, hemosiderin, and iron-containing prosthetic groups of proteins (e.g.,
heme, iron-sulfur complexes), whereas chelatable iron comprises free iron and
iron ...
Neil Kaplowitz, Laurie D. DeLeve,
2013
10
Hemochromatosis: Genetics, Pathophysiology, Diagnosis and ...
Chelatable iron Most of the body iron in normal subjects is unavailable for
chelation. Hemoglobin iron, representing more than two- thirds of all iron, is
resistant to DF chelation". Likewise, transferrin-bound iron is a very poor source
for in vivo ...
James C. Barton, Corwin Q. Edwards,
2000